Understanding the Mechanisms and Global Approach to Long COVID

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Researchers discuss the various mechanisms underlying long COVID, the influence of genetics and environmental factors, and the need for a global approach to understand its outcomes. They also highlight the challenges of recruiting diverse study participants due to decreasing long COVID cases and emerging SARS-CoV-2 variants, while emphasizing large-scale efforts in the US and Europe to find therapies.

Evidence so far suggests that the prevalence of long COVID in low- and middle-income countries could be similar to that of wealthier countries. For example, by some estimates, more than four million people in Brazil have long COVID.

However, an absence of research on the condition in less-wealthy countries has left advocates hamstrung: few physicians acknowledge that long COVID exists. A lack of data is also hampering efforts to search for the mechanisms of the condition and tailor treatments.

This is an audio version of our Feature Long COVID is a double curse in low-income nations — here’s why

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