A lot of people have looked at that and it number one doesn't make any difference. It's a way to stop taking omega threes before surgeries. The FDA on the high dose omega three drugs, like La Vasella or Vasipa say they do not increase risk for clinically significant bleeding.
Bill Harris, PhD is an internationally recognized expert on omega-3 fatty acids and fish oil. He has more than 300 publications relating to fatty acids, including omega-3s, in the medical literature.