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Adverse Childhood Experiences - HPA axis & Brain changes: cortisol, amygdala, hippocampus, cytokines, & epigenetics (Part 3 of ACE series)

Psychiatry & Psychotherapy Podcast

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Impact of ACEs on Brain White Matter and Connectivity

The chapter explores how Adverse Childhood Experiences affect white matter integrity in the brain, particularly in the corpus callosum and connectivity between brain regions, influencing responses to threatening stimuli. It also discusses the role of social connections in modulating fear responses and the importance of therapies like mentalization-based therapy in improving interpersonal relationships.

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