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Perspectives #19: Adaptation, Signaling, and Performance, with Andy Coggan

Empirical Cycling Podcast

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The Substantial Change in Metabolic Regulation in Muscle

The primary signal for muscle likes and breakdown actually resides within the contracting muscle itself. The metabolic milieu within the muscle once you inflate that cuff is exactly the same as it was right beforehand while they were exercising. ADP is high PI is high, phosphocreatins low AMP is elevated etc well it really shows that oxygen can be used to help a person swim better.

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