
TWiN 30: Gut to brain spread of alpha-synuclein in Parkinson's disease
This Week in Neuroscience
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Exploring Early Pathology Spread in Parkinson's Disease
This chapter explores the initial brain regions impacted by Parkinson's disease, particularly the olfactory bulb and the DMV. It revisits historical hypotheses on how Lewy body pathology may spread from sensory and digestive systems to the brain, comparing these pathways to those of other neurological disorders.
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