Jeans and Obesity - Are We Talking About Genes That Regulate Appetite?

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Most of the genes that have been found so far, when you look at their function, are associated with body fatness. But whether we're scratching the suface or we really have got a full picture, i don't think anyone quite knows. We still don't have very good methods of measuring metabolic rate or understanding how we burn caleries. So it could be that we're missing a lot because we don't, we can't identify those.

In Episode #224, I sit down with Dr Tim Spector to address the significance of eating for your specific biology. We discuss research on twins, exploring nature versus nurture; the role of the microbiome in health outcomes; and whether conditions such as obesity and Type 2 diabetes are genetic. Dr Spector also offers advice on adapting your diet to your specific needs.

When we place so much focus on population-level data for health outcomes, it can be easy to lose sight of the unique biology that defines the way each person interacts with food. Dr Tim Spector joins me today to discuss how personalised nutrition may be the key to unlocking the healthiest version of ourselves.

Specifically, we discuss:

Intro (0:00)
The Twin Study (2:33)
How Medicine Has Changed (7:24)
Obesity: Genetics & The Microbiome (13:30)
How much Genetics plays a role (23:36)
Zooming in on the Microbiome (32:36)
Big Picture (54:37)
Artificial Sweeteners (1:05:30)
Changing the Microbiome (1:14:58)
Blood Glucose (1:18:18)
Blood Lipids (1:26:40)
Vision for the Future (1:32:22)
Outro (1:35:45)

If you found this conversation informative, Dr Tim Spector has an abundance of resources and contact points available. To connect with Dr Spector, you can do so on Instagram and Twitter. Learn more about him and his books at https://tim-spector.co.uk/. Discover more about ZOE at https://joinzoe.com/.

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Enjoy, friends.

Simon

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Simon Hill, Msc, Bsc (Hons)

Creator of Theproof.com and host of The Proof with Simon Hill

Author of The Proof is in the Plants

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