The chapter explores the genetic influences on eating behavior in dogs, specifically focusing on the POMC gene mutation found in Labrador retrievers and flat-coated retrievers. The conversation delves into how this mutation affects food-seeking behavior and energy expenditure in dogs, shedding light on the challenges pet owners face in managing their dog's weight. Additionally, the chapter touches on the broader issues of pet obesity crisis and draws parallels between genetic factors influencing obesity in animals and humans.