CAR-T Recombinant T-Cells: A Cellular Therapy for Cancer

We will be discussing only the commercially available FDA-approved products. There's a broad range of other CAR-T recombinant T-cell, NK cells, and other cellular therapy products that are still in early or late investigations for a wide variety of conditions and indications. The basic principle for chimeric antigen receptors is to engineer this receptor in order to graft a defined specificity onto an immune-effector cell. And here we are specifically looking at its function against tumor cells.