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Nuances of CAR-T Therapy in Oncology
Exploring the complexities of CAR-T therapy in oncology, this chapter discusses efficacy differences among CAR-T treatments, challenges in patient treatment such as insurance barriers, and the importance of improving access for all patients. The speakers delve into the nuances of CAR-T therapy in the context of multiple myeloma, emphasizing the need for understanding car constructs and addressing health disparities in treatment. They also highlight concerns about secondary malignancies associated with genetic manipulation in CAR-T therapy and compare in vitro and in vivo therapies for optimal outcomes.