There’s a problem with billionaires at the moment. Every day, you make a hundred billion platelets. For some in our society, even that colossal quantity isn’t nearly enough. They strive ever onward for even more. Unfettered platelet production all the time forever - after all the number can only go up. But mo’ platelets leads to mo’ problems. Go on a journey with Bashar, Nick and Cale to learn how some patients can become the Bezos of platelets and accumulate more than you can possibly need or want. Don’t let us stop you having a tacky wedding though.
TIMESTAMPS
2:24 - Cutoffs (arbitrary as usual)
4:24 - Platelet biology
6:11 - TPO
7:53 - Spurious thrombocytosis
10:50 - Reactive thrombocytosis
12:30 - Blood loss and thrombocytosis
13:12 - TPO Kinetics
16:00 - Iron deficiency and thrombocytosis
19:10 - Hyposplenism
20:03 - Drugs
21:54 - MPNs
23:53 - Molecular Testing
25:27 - Clots AND Bleeds?!
26:58 - A General Approach
29:17 - Can we test TPO?
30:29 - Case Study
31:44 - Take Home Messages
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