[Archive] Of Ticks, Alpha-gal, and Red Meat Allergies
The Curious Clinicians
Alpha-Gal: Ticks, Meat Allergy, and Xenotransplantation
This chapter explores the molecule alpha-gal, its absence in humans, and how lone star ticks can transfer it to humans, potentially causing allergic reactions to red meat. It delves into the evolution of why humans lack alpha-gal and the theories behind how ticks acquire it. The conversation also touches on cetuximab allergic reactions and the challenges of xenotransplantation due to the presence of alpha-gal in animal organs transplanted into humans.
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