10min chapter

The Curious Clinicians cover image

[Archive] Of Ticks, Alpha-gal, and Red Meat Allergies

The Curious Clinicians

CHAPTER

Alpha-Gal: Ticks, Meat Allergy, and Xenotransplantation

This chapter explores the molecule alpha-gal, its absence in humans, and how lone star ticks can transfer it to humans, potentially causing allergic reactions to red meat. It delves into the evolution of why humans lack alpha-gal and the theories behind how ticks acquire it. The conversation also touches on cetuximab allergic reactions and the challenges of xenotransplantation due to the presence of alpha-gal in animal organs transplanted into humans.

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