The Importance of Timing in Acetaminophen Overdoses

When you look into anything with a acetaminophen overdose, they're going to talk about nomograms or your acetaminophen levels. The RUMAC Matthew nomogram is incredibly sensitive predictor for an AST greater than a thousand. In the US, we don't use the 200 line because when the group wanted to study a single 15 in the US, the FDA said, okay, but you need to add a buffer of 25%.