Best of Series - The Crucial Role of NAD+ in Optimal Health
Dr. Joseph Mercola - Take Control of Your Health
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The Effects of CD38 on NAD Production
Every time PARP is activated for DNA repair, it consumes 150 NAD molecules. Another enzyme called CD38 does consume about 100 molecules of NAD for every cycle of its reaction. Even if you can inhibit CD38 by just a very, very small amount, you can have a significant impact on NAD levels because it is so inefficient.
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