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The Historical Origins of Parkinson's Disease
This chapter explores the historical origins of Parkinson's disease, discussing its recognition in ancient civilizations and referencing works by Leonardo da Vinci, Shakespeare, and Thomas Hobbes. It delves into the life of James Parkinson, the paleontologist who potentially described appendicitis and gave his name to the disease. The chapter also discusses the contributions of Jean-Martin Charcot, who further characterized the symptoms and hypothesized the origin of Parkinson's in the substantia nigra.