The Structure of Heroin

Heroin is two to three times more potent than morphine because of the extended half-life. It's metabolized primarily in the liver, but also a little bit in the brain as well. When you take the drug orally, like morphine, it goes through the liver, which adds compounds to the molecule and starts metabolizing it. So how much you're actually getting an experience with heroin will be very different if you smoke or inject it.