
The Biology of Health & Longevity | Top Expert Insights from 2025
Live Well Be Well with Sarah Ann Macklin | Health, Lifestyle, Nutrition
Creatine timing and health effects
Stacy clarifies creatine requires saturation, aids recovery, gut integrity, and mood over weeks, not immediate timing.
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As we wrap up another incredible year of Live Well Be Well, I found myself asking one simple question. What truly stayed with me?
In this conversation, I’m joined by world-leading voices who helped shape some of the most meaningful discussions of 2025, including:
Dr. Stacy Sims, exercise physiologist redefining how women should train, fuel, and recover
Dr. Andy Galpin, performance scientist translating elite physiology into everyday health
Doug Evans, longevity thinker exploring how nutrition and lifestyle shape long-term vitality
Dr. Iñigo San Millán, physiologist uncovering the role of mitochondria in metabolic health and endurance
Jason Van Blerk, founder of Human Garage, offering a new lens on fascia, movement, and healing
This episode is a reflection not only on science, but on perspective. Across these conversations, a shared message emerged. Our bodies are not machines to override. They are intelligent systems that respond to care, context, and consistency.From female specific physiology and metabolic flexibility to recovery, fascia, and longevity, these voices bring clarity to a crowded wellness space. Together, they remind us that sustainable health is built through understanding rather than optimisation alone.
Here’s What We Dive Into:- How female physiology changes the way women should train, fuel, and recover.
- Why performance science must move beyond one size fits all advice.
- What metabolic flexibility really means and why it matters beyond elite sport.
- How mitochondrial health underpins energy, endurance, and long term wellbeing.
- Why recovery is an active biological process, not simply rest.
- What fascia reveals about pain, movement, and whole body connection.
- How modern lifestyles disrupt our biology and what helps restore balance.
- Why longevity depends more on fundamentals than shortcuts.
Love,
Sarah Ann 💛
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This episode is sponsored by:NOWATCH: The compassionate health trackerConnecting body and mind with unique stress recovery insights so you can live fully today15% off with code LWBW15 at nowatch.com
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00:00:00 The question that shaped this year end reflection
00:04:18 Female physiology and outdated fitness narratives
00:09:42 Performance science beyond extremes
00:15:06 Metabolic flexibility explained simply
00:20:31 Mitochondria and sustainable energy
00:26:47 Recovery as a biological skill
00:32:10 Fascia, pain, and whole body communication
00:37:58 Longevity through fundamentals
00:43:21 What listening to the body really means
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