What's the Best Time of Day to Take a Supplement?

This can really help us to determine what might be the best time of day to take a certain supplement, depending how long we notice the perceivable effects. Usually when i do it, after about two or three hours i will have like a cup of coffee and some food, and just some normal lunch. But usually i will not take anything else that day. Just maintain that semi blanks late for most of the day,. sometimes though, which is really interesting. Sometimes i'll take something that completely negates the need for any coffee, which is also interesting. And those are just kind of small anomalies that happen consistently that you can find here and there and determine and then see how that effects