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Freely Filtered 042: Nephrin Antibodies Cause Minimal Change Disease. Wait...What?

Freely Filtered, a NephJC Podcast

CHAPTER

Endothelial Inflammation - Is There a Circulating Factor?

In order to have acute and frotic syndrome, you need one effacement of photosites. You're moving from a small porous system with lots of tiny little pores to a large, poor system. And so the negative charge of the endothelium no longer works to repel negatively charged albumin. When you have enough pressure, it'll be forced through.

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