11min chapter

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#312 - A masterclass in lactate: Its critical role as metabolic fuel, implications for diseases, and therapeutic potential from cancer to brain health and beyond | George A. Brooks, Ph.D.

The Peter Attia Drive

CHAPTER

Lactate as a Brain Fuel: Unraveling Metabolic Roles

This chapter explores the innovative methodologies used to investigate lactate's role as a metabolic fuel for brain function, particularly after injuries. It discusses the implications of lactate infusion versus glucose metabolism in traumatic brain injury patients and the potential of lactate as a superior energy source for neurons. Additionally, the chapter highlights technical challenges in using advanced imaging techniques to better understand lactate's therapeutic effects in brain recovery.

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