Auto-inflammatory Diseases: Presentation, Diagnosis, and Treatment

This chapter explores the presentation, diagnosis, and treatment of auto-inflammatory diseases, which are disorders of innate immunity driven by overproduction of inflammatory cytokines. It discusses the challenges of diagnosing these rare diseases and emphasizes the importance of paying attention to elevated inflammatory markers during episodes of inflammation. The chapter also covers common auto-inflammatory syndromes, including familial Mediterranean fever and mavalonic kinase deficiency.