Effects of Omega-3s on Testosterone and LDL Cholesterol Levels

This chapter explores the impact of omega-3s on testosterone and LDL cholesterol levels, discussing the Apo-E allele genotype and its relationship to triglyceride lowering. The potential mechanisms of DHA and Apo-E4, as well as the minimal changes in LDL and HDL levels, are also examined, questioning the clinical significance of nutragenomics.

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Dr. Gillett and Nurse Practitioner James O'Hara delve into a conversation addressing the potential risks associated with omega-3 fatty acids.

00:00 Introduction

00:12 Emerging Risks Associated with Omega Fatty Acids

5:41 Synthesizing Insights from Four Significant Randomized Trials

16:00 Insights from Animal and Canine Studies

18:51 Examination of a DHA-Specific Trial

20:13 Addressing the Adequacy of a 500mg EPA Dosage

22:39 Exploring the Field of Nutrigenomics

24:57 Findings from a Cod Liver Oil Study

25:53 Investigating Blood Viscosity Concerns

27:13 Focusing on DHA Exclusive Trials

30:10 Unraveling the Link between Omega Fatty Acids and Gum Recession

30:43 Contrasting DHA versus EPA

31:41 Impact of Oxidized Fish Oil

37:54 Closing Thoughts and Outro

Studies/References

► https://www.jacc.org/doi/epdf/10.1016/j.jacc.2023.05.024

► https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.120.052209

► https://jamanetwork.com/journals/jama/fullarticle/2773120

► https://pubmed.ncbi.nlm.nih.gov/30415628/

► https://www.nejm.org/doi/pdf/10.1056/NEJMoa1811403?articleTools=true

► https://www.acc.org/clinical-topics/arrhythmias-and-clinical-ep/~/media/67142EC297834666B0CF741690027D9D.pdf

► https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.107.712984

► https://www.jstage.jst.go.jp/article/circj/86/5/86_CJ-21-0615/_pdf

► https://www.ahajournals.org/doi/pdf/10.1161/CIRCEP.112.971515

► https://pubmed.ncbi.nlm.nih.gov/2694923/

► https://pubmed.ncbi.nlm.nih.gov/18779276/

► https://pubmed.ncbi.nlm.nih.gov/17490962/

► https://pubmed.ncbi.nlm.nih.gov/2685599

► https://pubmed.ncbi.nlm.nih.gov/12145002/

► https://pubmed.ncbi.nlm.nih.gov/18555744/

► https://pubmed.ncbi.nlm.nih.gov/24970858/

► https://pubmed.ncbi.nlm.nih.gov/29846653/

► https://www.deepdyve.com/lp/wiley/effect-of-packaging-and-encapsulation-on-the-oxidative-and-sensory-ElE1I6yjXd?key=dd_plugin&utm_campaign=pluginGoogleScholar&utm_source=pluginGoogleScholar&utm_medium=plugin

► https://doi.org/10.1080/19390211.2023.2252064

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