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Exchanges at the Frontier: 08Feb14 - Bonnie Bassler

World Questions

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Manipulating Bacterial Behavior: A Potential Alternative to Antibiotics

This chapter explores the possibility of modifying bacterial behavior by interfering with their quorum sensing instead of directly killing them with antibiotics. It discusses the strategies for targeting bacteria in the human body, including narrow-spectrum and broad-spectrum therapies. The chapter also delves into the potential of enhancing the activity of beneficial bacteria to combat disease and the challenges involved in treating polymicrobial infections.

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