Unlocking the Science of Aging: How to Eliminate ‘Zombie Cells’ for Longevity and Vitality | Dr Gregory Kelly
High Performance Health
Understanding Cellular Aging and the Role of Senolytics
This chapter explores cellular aging, focusing on the role of senescent or 'zombie' cells and how moderate stress can enhance autophagy for cell repair. Additionally, it introduces a groundbreaking compound aimed at rejuvenating cells, analogous to a gardener tending to plants for optimal growth.
Angela presents the second of a two part conversation with Dr Gregory Kelly, in which they discuss the intriguing topic of senescent cells, often referred to as "zombie cells." These cells accumulate with age, resist apoptosis, and contribute to inflammation, negatively impacting overall health and vitality.
Dr. Kelly explains the mechanisms behind cellular senescence and introduces the concept of senolytics—compounds designed to help clear these dysfunctional cells from the body
KEY TAKEAWAYS
- What Are Senescent Cells?: Learn about cells that resist death, use up resources, and create inflammation, contributing to aging.
- Senolytics in Action: How senolytic compounds remove 'zombie cells' and promote tissue health.
- Benefits of Intermittent Dosing: Why senolytics are taken just twice a month and how they enhance long-term health.
- Key Ingredients for Longevity: Explore the unique properties of fisetin, quercetin, curcumin, and more in supporting joint, brain, and overall health.
- Practical Applications: How senolytics can help with joint discomfort, muscle health, and improving energy levels.
TIMESTAMPS AND KEY TOPICS
- 0:04 – Understanding cellular apoptosis and 'zombie cells.'
- 3:38 – What senescent cells are and their role in aging.
- 9:28 – Hormetic stress and reducing cellular senescence.
- 11:20 – The science behind senolytics and intermittent dosing.
- 14:27 – Using senolytics to 'prune' unhealthy cells.
- 18:07 – When and how to take senolytics effectively.
- 23:18 – Benefits of senolytics for joints, energy, and inflammation.
- 27:34 – Exploring key ingredients like fisetin, quercetin, and curcumin.
- 35:12 – Addressing anabolic resistance and improving muscle health.
- 44:39 – Best age to start using senolytics for long-term benefits.
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ABOUT THE GUEST
Dr. Gregory Kelly is a naturopathic physician (N.D.). He is Vice President of Product Development at Qualia Life Sciences and author of the book Shape Shift. He was an editor of the journal Alternative Medicine Review and has been an instructor at the University of Bridgeport in the College of Naturopathic Medicine, where he taught classes in Nutrition and Counseling Skills. Dr. Kelly has published numerous articles on various aspects of natural medicine and nutrition, contributed three chapters to the Textbook of Natural Medicine, and has more than 30 journal articles indexed on Pubmed. His areas of special interest and expertise include nootropics, anti-aging and regenerative medicine, weight management, and the chronobiology of performance and health.
ABOUT THE HOST
Angela Foster is an award winning Nutritionist, Health & Performance Coach, Speaker and Host of the High Performance Health podcast. A former Corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela has been featured in various media including Huff Post, Runners world, The Health Optimisation Summit, BrainTap, The Women’s Biohacking Conference, Livestrong & Natural Health Magazine.
Angela is the creator of BioSyncing®️ a blueprint for ambitious entrepreneurial women to biohack their health so they can 10X how they show up in their business and their family without burning out. Angela’s BioSyncing®️ Blueprint is currently closed. Click here to get on the waitlist.
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