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Ep. 23: “Dendritic Cells and the Immune System” Featuring Dr. Caetano Reis e Sousa

The Immunology Podcast

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The Role of Dendritic Cells in Immunity and Cross-Presentation of Antigens

The chapter delves into the importance of dendritic cells in the immune response, exploring their role in sustaining immunity to pathogens like influenza. It discusses a study on a receptor in dendritic cells that binds to dead cell remnants, aiding in antigen presentation and potentially impacting anti-cancer immunity. The chapter also touches on mechanisms of cross-presentation, including the role of the NGR-1 receptor in promoting the rupturing of phagosomes for antigen access.

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