Diagnosing Multiple Sclerosis: Imaging and Immunology Insights

This chapter explores the immunologic and radiologic aspects crucial for diagnosing Multiple Sclerosis (MS), focusing on the role of B cells and specific brain lesions. It covers the diagnostic criteria, including the importance of imaging techniques like T2 flare images, and discusses the limitations of the McDonald criteria. Additionally, the chapter highlights the significance of lumbar punctures and CSF analysis in confirming MS and the implications of various lesion characteristics on clinical symptoms.