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Dmitry Kats, PhD: From Niatonin to Niacur

Mastering Nutrition

CHAPTER

The Role of pH in TRP Activation

The pH is it's, you know, I think that it's or wait a second. So were you trying to say that when the intracellular pH is too high, the cell will import more niacin to acidify it and that will activate the TRP V one? That's what this paper says. But that doesn't show that if you that if you increase the pH in the cell, you increase the transport of nikatineic acid into it. Did they show that? No, they weren't able to see that. Right. And that's why like tissue damage, for example, could cause that would be part of the mechanism between tissue damage and pain

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