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Why you should test ApoB | Dan Soffer, Md

The Proof with Simon Hill

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Understanding Atherogenesis: From Roots to Complexities

This chapter explores the historical evolution of atherogenesis, from early cholesterol hypotheses linked to dietary changes to modern theories emphasizing endothelial injury. It examines the multifactorial nature of cardiovascular disease, discussing the roles of hypertension, smoking, and genetics alongside lipoproteins in atherosclerosis development. The chapter also sheds light on the interactions between lipoproteins and the arterial wall, detailing how they penetrate the endothelium and initiate inflammatory processes contributing to cardiovascular disease.

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