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A PhD's Secret Weapon: The Four Biomarkers Every Expert Should, But Doesn’t, Analyze

Mastering Nutrition

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Redox Reactions and NAD+/NADH Ratio

This chapter discusses redox reactions and the concept of redox couples, specifically focusing on the NADH and NAD+ redox couple. It explains that the NADH to NAD+ ratio represents the redox state of a cellular compartment, and that a higher ratio indicates a more reduced state while a lower ratio indicates a more oxidized state. The chapter also explores the relationship between the lactate to pyruvate ratio and the beta-hydroxybutyrate to acetoacetate ratio as release valves for the pressure building up within the NADH to NAD+ ratio.

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