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EB. 114: Fat-Burning Drives Insulin Resistance And Eating Carbohydrates Improves Insulin Sensitivity

The Energy Balance Podcast

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Understanding the Role of Glucagon in Metabolic Dysfunction

This chapter explores the significant impact of glucagon on elevating blood glucose levels in conditions like diabetes and obesity, emphasizing its contribution to insulin resistance and metabolic dysfunction. It discusses how stress hormones can upregulate glucagon levels even in low carb eaters, shedding light on the connection between glucagon, insulin resistance, and diabetes pathology. The chapter also touches on the effects of fasting on glucagon levels, highlighting its role in promoting gluconeogenesis and ketogenesis, ultimately affecting insulin sensitivity and glucose tolerance.

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