Daniel's path: astrophysics to global quant

How do you start a hedge fund—and where should you launch it? Daniel Xystus has done both. From Los Angeles quant to Chicago portfolio manager to CIO in Hong Kong and the Middle East, Daniel now helps new hedge fund managers navigate fund setup, regulation, and operations. We break down what it really takes to launch a hedge fund—choosing your fund domicile, building professional infrastructure, and avoiding the operational mistakes that quietly kill most funds. Daniel explains how fund structures like Cayman, UCITS, and Singapore’s VCC differ, and why getting operations, compliance, and risk management right often matters more than alpha generation itself.We also explore how global macro and quantitative trading strategies adapt across regions—from Asia ex-Japan markets to Dubai and Abu Dhabi investment funds. Daniel breaks down how Asia hedge funds deal with high shorting costs, liquidity issues, and regulatory complexity, and why Middle East family offices are emerging as powerful allocators. From Hong Kong’s finance hub to the rising Singapore hedge fund industry, Daniel shares lessons from running billion-dollar books and advising allocators worldwide—and what aspiring quants should understand about risk, execution, and building something durable in global markets.We also discuss...Why most hedge funds fail because of operational issues, not bad tradesHow to pick the right hedge fund domicile for your investorsWhat to know about hedge fund regulations and compliance when launching a fundCommon hedge fund mistakes made by first-time managersHow to evaluate fund administration, legal structure, and prime broker supportThe real difference between long-only, market-neutral, and global macro investingHow liquidity, FX exposure, and regional risk shape Asia ex-Japan strategiesWhy Middle East family offices are allocating more to alternative investmentsHow quant funds integrate portfolio construction, risk models, and execution systemsBuilding quantitative trading strategies that survive real-world transaction costsThe role of backtesting strategies in validating hedge fund modelsWhat global allocators look for before investing in Asia hedge fundsThe rise of the Dubai finance hub and Singapore hedge fund industryHow Hong Kong’s finance hub is evolving post-COVIDCultural and regulatory differences between running funds in the U.S., Asia, and the Middle EastLessons from Daniel’s transition from astrophysics to finance and global fund management00:00 Intro & special request01:49 How to start a hedge fund02:49 Why hedge funds fail operations and structure04:29 Common hedge fund mistakes new managers make05:49 Hedge fund operations and regulation explained07:19 Asia hedge funds shorting costs and liquidity08:49 Quantitative trading strategies and backtesting systems10:19 Choosing your fund domicile Cayman vs VCC12:19 Hedge fund structure explained for allocators13:49 Launching a fund in Asia ex-Japan markets15:29 Portfolio construction and risk management insights17:19 Building an Asia-focused long short strategy18:49 Emerging markets liquidity Philippines case study20:49 From astrophysics to quant hedge fund career23:19 Running billion-dollar portfolios across global markets24:49 Global macro investing in Asia and MENA26:49 Inside Hong Kong’s post-COVID finance hub28:49 Dubai and Abu Dhabi investment fund growth31:19 Middle East family offices and capital flows33:19 Comparing hedge fund regulation across regions34:49 Dubai and Abu Dhabi as finance centers36:49 Cost of living and taxes for quants38:49 Best cities for hedge fund opportunity40:19 Quant trading lessons on risk and psychology42:49 Closing thoughts building global hedge funds