The Role of Epigenetic Modifications in Lupus and the Hippo Signaling Pathway

This chapter explores the role of epigenetic modifications in lupus, with a focus on the skin. The speakers discuss the hippo signaling pathway and its relevance in lupus, highlighting the differential methylation of WWC1 gene. They also delve into the functional impact of differential gene expression in lupus keratinocytes, particularly in response to UV light, and the potential use of kinase inhibitors for treating photosensitivity in patients.