Immune 77: Squeezing the most killing out of neutrophils
Immune
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Enhanced Neutrophil Antibacterial Killing Mechanisms
Exploration of how neutrophils improve bacterial killing without increased phagocytosis but through ROS production. Experiments manipulating pore sizes and genetic modifications in mice reveal the impact on antibacterial killing. Discussion on squeezing neutrophils, changes in endothelial cells, and importance of PZO1 channel activation in enhancing neutrophil function.
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