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iwNHL 2023 Session IV: Novel therapies in NHL: BTK inhibitors, BTK degraders, and bispecific antibodies

VJHemOnc Podcast

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Lessons from a First-in-Class Bispecific Therapy and its Implications for Lymphoma Treatment

This chapter discusses the lessons learned from a first-in-class bispecific therapy approved almost 10 years ago, including the success in earlier treatment lines, effectiveness in certain types of lymphoma, and the need to address residual cells and T-cell compartments. It also emphasizes considering T-cell exhaustion and dysfunction in combination strategies and the potential benefits of treatment-free intervals.

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