The Use of Methadone as an Analgesic Drug in Intraoperative Anesthesia

This chapter explores the benefits of using methadone as a long-acting medication for pain relief during and after surgery, while minimizing the need for additional opioids. It discusses the unique characteristics of methadone and its advantages over classical mu-opioid agonists. Additionally, it addresses concerns about tolerance and the use of methadone in conjunction with SSRIs.