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Cholesterol, metabolic health and heart disease | Dr Alan Flanagan and Danny Lennon

The Proof with Simon Hill

CHAPTER

Is There a Risk of LDL Denialism?

Paul Saladino: There's a concept of residual risk, right? We take someone with high LDL and they've got all these other stuff. They've got high triglycerides. They'veGot high inflammation, right? LDL comes in all of the interventions that we have. The target still is LDL coming down first; then you've got residual risk if someone still has high triglycerides because their LDL is low. And so what you saw in that trial was that in patients who achieved neither getting their LDL under 70 milligrams or getting CRP under two milligrams per liter, they didn't really have much of a risk reduction. But at that point, those individuals will benefit from

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