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How a key Alzheimer's gene wreaks havoc in the brain

Nature Podcast

CHAPTER

Can Cyclodextrin Reduce Myelination?

The team turned to a mouse model of Alzheimer's disease. They tried a drug that promotes cholesterol transport, cyclodextrin. And there, voila, we saw a significant decrease in the cholesterol accumulation inside this ApoE4 algorithm nuclei. The obvious question then is, could this drug have therapeutic potential? It has potential.

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