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Exploring the Evolving Hallmarks of Aging
This chapter delves into the expansion of the Hallmarks of Aging list to include new processes like inflammation, disabled autophagy, and microbiome dysbiosis, shedding light on the complex mechanisms of aging. It highlights the impact of mitochondrial dysfunction, cellular senescence, lysoproteostasis, and intercellular communication on cellular health and aging. The speaker proposes a comprehensive approach to address all aging hallmarks concurrently, challenging the conventional strategy of targeting individual mechanisms for therapeutic interventions.