#038 Dr. Guido Kroemer on Autophagy, Caloric Restriction Mimetics, Fasting & Protein Acetylation
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Nerve Degenerale Diseases
Most known nedegeneral diseases are either caused by the aggregation of e poorly built potents that somehowa create a potein aggregates at ar toxic for the cell. Or they can also be caused by subtle deficiencies in the autopagic and lisosomalmachineries that lead to the accumulation of unfolded potents at the end. So one strategy to treat no generation at least theoretically, is to increase autophagic turnover. And so er one technique is actually then to stimulate general autopegy by increasing the demand, by starvation, or by biochemical tricks that substitute for starvation.
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