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The Science of Virus Synthesis in Two Thousand and Five
The first instructions, the first detailed priticle for assembling influenza virus, was published in 19 99. The first virus was synthesized from synthetic dina in two thousand two and that was poleo virus which is probably comparable to, maybe slightly easier to assemble than influenza. And when there's a non trivial chance of millions, or even tens of millions of people dying, well, some discretion would seem prudent.