After facing rejection we often feel that our actions had no impact. They didn't produce the desired effect. As a result we lose hope in situations and it can really kind of get us down. This is often stronger for people with rejection, sensitivity, disorder or dysphoria. There are some people who experience this much more intensely than others. It actually leads to them being fearful of rejection so much so that they avoid situations out of fear of rejection. Individuals with high rejection sensitivity have a greater physical response to those feelings including intense anxiety and discomfort.