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Behind the Study: Molecular Dialogue Between Tumor Cells and Fibroblasts

Oncotarget

CHAPTER

Exploration of the Molecular Interactions Between Cancer Cells and Fibroblasts in Breast Cancer

Exploring the intricate relationship between cancer cells and fibroblasts, focusing on the pivotal role of cancer-associated fibroblasts (CAFs) in driving tumor growth, angiogenesis, and metastasis through gene and protein expression like osteopontin. The chapter also touches on the transformation of fibroblasts into myofibroblasts and its diverse effects on tumor development across various cancer types.

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