Hyperchloric Versus Isocaloric?

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When you eat sugar, it will increase fat stores if you take it out long enough. The high glycemic carbs are working by making fructose. If we block fructose metabolism with an inhibitor or like with a knockout, we can block the development of fatty liver from glucose. This is important because several companies, large pharma are working on making fructose kinase inhibitors. And what's great about them is they will block the development Of diabetes,. These fructose inhibitors from both high glycemiccarb as well as from fructose. So it's fructose that's driving it, but the food could be high glycemic carbohydrates.

Episode #233. Dive deeper into how saturated fats and sugar affect metabolism and the liver in this conversation with Dr Richard Johnson. The Proof community had many questions after Dr Johnson’s appearance on Episode #215, and we return today to answer them: What does human outcome data say? What are the risks of the keto diet and high blood sugar? Do our opinions align?

We answer these questions and more, addressing:

Intro (0:00)
Dr. Johnson’s Thesis on Fructose (3:27)
Gaps in Current Studies (11:28)
Saturated Fat Versus Sugar (20:20)
Long-term risk of Keto Diet (33:09)
Fructose Effect on Saturated Fat (36:28)
Survival Mechanisms (40:40)
Type of Fat (46:37)
Metabolic Health & Fructose (53:00)
Role of the Liver (1:02:20)
Problem with High Blood Sugar (1:09:15)
Triglycerides & Uric Acid (1:17:22)
When Fatty Liver Happens (1:27:52)
Ceramides (1:31:45)
Outro (1:33:30)

To connect with Dr Richard Johnson, you can find him on Instagram and Twitter, or learn more on his website. For a more comprehensive picture of Dr Johnson’s stance, make sure to check out his book, Nature Wants Us To Be Fat.

Discover additional resources, supporting studies, and more insights in the full show notes.

Enjoy, friends.

Simon

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Simon Hill, Msc, Bsc (Hons)

Creator of TheProof.com and host of The Proof with Simon Hill

Author of The Proof is in the Plants

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