The Impact of Omicron Spike on Immune Response to the Original Vaccine

The concern is different from what we've been talking about with influenza. Because influenza, you're thinking about changing the vaccine to match the current strain going around. We had the original vaccine, and then we were using it for a really long time. And then we were still using it even when we knew that new variants have come out that are evading the antibodies that were generated from that. So instead of moving to a new vaccine where you're better matched to the variants that are currently circulating, we just lumped it together with the original one.