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The Positives and Negatives to Progesterone
There's a general pro-inflammatory response where the immune system is kicking in like, you know, things that are the less healthy type of immunity. And then on the other hand, it's also just generally elevating the immune system to break down these tissues that it wants to break down. If we're looking at trying to have greater heat tolerance, so women have a decrease in the amount of heat tolerance they have and can have a higher heat load per workload than men. progesterone drives core temperature up by about 0.5 degrees C when it comes out. So you have shorter time to fatigue because of the heat.