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Fluid Therapy for Critically Ill Adults With Sepsis

JAMA Clinical Reviews

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The Role of Fluid Diffusion in Critical Care Medicine

Dr. Fernando Zampere: It's conceivable that if you give a lot of fluids very fast, it may actually increase tissue edema and maybe that could be related to worse outcomes. So we tested that hypothesis in the basic trial. We compared chili fusion rates for fluid bozos in critically ill patients. And results for the primary endpoint at nine days were neutral.

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