21min chapter

The Peter Attia Drive cover image

#272 ‒ Rapamycin: potential longevity benefits, surge in popularity, unanswered questions, and more | David Sabatini, M.D., Ph.D. and Matt Kaeberlein, Ph.D.

The Peter Attia Drive

CHAPTER

Unraveling Rapamycin: A Journey Through mTOR Research

This chapter explores the historical and scientific journey of rapamycin and its interaction with the mTOR protein complex, shedding light on the balance between growth and breakdown in human physiology. It discusses the ongoing research into rapamycin’s potential implications for longevity and its effects across various species, including a veterinary trial in dogs. The conversation highlights the importance of scientific integrity in aging research while assessing both basic and applied research in understanding the benefits of rapamycin.

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