The flu shot doesn't work as well on people who don't have adequate sleep. People who aren't sleeping well or people under significant stress, that they'll have a blunt to the immune response. And asking your body to make an immune response from a shot is not a really natural thing for your body to do. So if there are factors in which we've talked about, which are negatively affecting your immune system or stressing your immune system, that will impair your ability to mount that response to the to the vaccine.

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