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14min chapter
Immune 81: T cells and tolerance with Joseph Larkin III
Immune
Exploring Regulatory T Cells and Autoimmune Diseases in Mouse Models
The chapter focuses on the lab's research on regulatory T cells and their impact on autoimmune diseases through studies in mouse models, particularly lupus. It discusses the interaction between regulatory T cells, conventional T cells, and suppressors of cytokine signaling, emphasizing their role in controlling immune responses. Additionally, the chapter covers research on the SOX1 gene, cytokine production, signal transduction pathways, and potential treatments for autoimmune conditions like uveitis.
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