22min chapter

The Tim Ferriss Show cover image

#650: Dr. Matthew Walker, All Things Sleep — How to Improve Sleep, How Sleep Ties Into Alzheimer’s Disease and Weight Gain, and How Medications (Ambien, Trazodone, etc.), Caffeine, THC/CBD, Psychedelics, Exercise, Smart Drugs, Fasting, and More Affect Sleep

The Tim Ferriss Show

CHAPTER

Sleep, Alzheimer's, and Cognitive Health

This chapter examines the critical link between sleep and Alzheimer's disease, detailing how sleep deprivation exacerbates the accumulation of toxic proteins like beta amyloid and tau. The discussion highlights groundbreaking research on the brain's glymphatic system, revealing its role in clearing these proteins during deep non-REM sleep, and emphasizes the importance of enhancing sleep quality as a preventive measure against cognitive decline. Additionally, the chapter addresses gender differences in sleep patterns and the evolutionary significance of sleep across species, showcasing sleep as a fundamental biological necessity.

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