Pregnenolone: The Hormonal Key to Mental Health

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Dr. James and I dive deep into the often-overlooked dangers of low cholesterol, its impact on mental health, and why our bodies—and especially our brains—need dietary fat. We also discuss the connection between modern diets, rising suicide rates, and why functional psychiatry may hold answers that traditional models miss. Make sure to listen to the full interview to learn more.

Dr. James Greenblatt is a board-certified child and adult psychiatrist with over 35 years of clinical experience. He bridges traditional psychiatry with integrative and functional approaches to mental health, focusing on biochemical individuality and root-cause healing. Dr. Greenblatt has authored several books and is a pioneer in nutritional psychiatry, working to transform how we approach mental health conditions like depression, ADHD, and eating disorders.

We discuss the following:

• All about Dr. James Greenblatt  
• Why cholesterol matters   
• Cholesterol and eating disorders   
• Low mood from lack of protein and fatty acids
• Military study on fatty acid deficiency   
• Suicide risk: causes and factors   
• How statins affect the body   
• Low cholesterol and suicide risk   
• Role of pregnenolone   
• Why hormones are commonly prescribed   
• Gut health and depression link   
• Is depression increasing?   
• Where to find Dr. James Greenblatt 

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EPISODE RESOURCES

• Website
• Instagram
• Facebook
• Functional Medicine Courses
• Psychiatry Redefined
• Finally Focused book
• Gender Changes in Frogs Exposed to Atrazine (in waters)
• Stains and suicidal ideation
• Military and Omega 3s

• Personalized Health Plan
• CIRS Testing
• DUTCH Complete Hormone Panel
• Complete Wellness Panel
• OMAPREM SPM Resolvins Fatty Acids

Other Low Cholesterol Studies: 

• https://pubmed.ncbi.nlm.nih.gov/15555697/
• https://pubmed.ncbi.nlm.nih.gov/8071280/ 
• https://pubmed.ncbi.nlm.nih.gov/26505144/
• https://pmc.ncbi.nlm.nih.gov/articles/PMC3671696/ 
• https://pmc.ncbi.nlm.nih.gov/articles/PMC4688029/ 
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